Adenylate Cyclase 1, Brain (ADCY1) Antibody
312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Adenylate Cyclase 1, Brain (ADCY1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx124162
tested applications
WB
Description
ADCY1 Antibody is a Rabbit Polyclonal Antibody against ADCY1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adenylate Cyclase 1, Brain (ADCY1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q08828 |
| Gene ID | 107 |
| NCBI Accession | NP_066939.1 |
| Alias | AC1,DFNB44,ATP pyrophosphate-lyase 1 |
| Background | Antibody anti-ADCY1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ADCY1 is a membrane-bound enzyme predominantly expressed in the brain, specifically in neuronal tissues. It is activated by G-protein-coupled receptors (GPCRs) and regulated by calcium/calmodulin, playing a vital role in generating cyclic AMP (cAMP), a second messenger critical for signal transduction. ADCY1 is essential for synaptic plasticity, learning, and memory processes. Dysregulation of ADCY1 has been linked to neurological disorders, such as cognitive impairments and epilepsy, due to impaired cAMP signaling pathways. Its expression and activity are crucial for calcium-dependent cAMP production in neurons.
Related Products
Human ADCY1(Adenylate cyclase type 1) ELISA Kit
Ver Producto
anti- ADCY1 antibody
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels(By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina(By similarity).
Ver Producto
Adenylate Cyclase 1, Brain (ADCY1) Antibody
Rabbit polyclonal antibody against ADCY1 protein. Immunogen region is Internal.
Ver Producto