Adenylate Cyclase 1, Brain (ADCY1) Antibody
637€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Adenylate Cyclase 1, Brain (ADCY1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx110846
Tested Applications
ELISA, WB
Description
Adenylate Cyclase 1 (Brain) Antibody is a Rabbit Polyclonal antibody against Adenylate Cyclase 1 (Brain).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase 1, Brain (ADCY1) Immunogen: Human ADCY1. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | 0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q08828 |
| Gene ID | 107 |
| OMIM | 103072 |
| Alias | AC1,DFNB44,ATP pyrophosphate-lyase 1 |
| Background | Antibody anti-ADCY1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY1 is a membrane-bound enzyme predominantly expressed in the brain, specifically in neuronal tissues. It is activated by G-protein-coupled receptors (GPCRs) and regulated by calcium/calmodulin, playing a vital role in generating cyclic AMP (cAMP), a second messenger critical for signal transduction. ADCY1 is essential for synaptic plasticity, learning, and memory processes. Dysregulation of ADCY1 has been linked to neurological disorders, such as cognitive impairments and epilepsy, due to impaired cAMP signaling pathways. Its expression and activity are crucial for calcium-dependent cAMP production in neurons.
Productos relacionados
Adenylate Cyclase 1, Brain (ADCY1) Antibody
Rabbit polyclonal antibody against ADCY1 protein. Immunogen region is Internal.…
Ver producto Adenylate Cyclase 1, Brain (ADCY1) Antibody
Adenylate Cyclase 1 (Brain) Antibody is a Rabbit Polyclonal antibody against Adenylate Cyclase 1 (Brain).…
Ver producto
Adenylate Cyclase 1, Brain (ADCY1) Antibody
ADCY1 Antibody is a Rabbit Polyclonal Antibody against ADCY1.…
Ver producto