Human Adenylate Cyclase 1, Brain (ADCY1) CLIA Kit
845€ (96 tests)
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935106861
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name
Human Adenylate Cyclase 1, Brain (ADCY1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492673
tested applications
CLIA
Description
Human ADCY1 Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Adenylate Cyclase 1, Brain (ADCY1) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.781 ng/ml - 50 ng/ml |
| Sensitivity | < 0.29 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AC1,DFNB44,ATP pyrophosphate-lyase 1 |
| Background | CLIA Kits ADCY1 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADCY1 is a membrane-bound enzyme predominantly expressed in the brain, specifically in neuronal tissues. It is activated by G-protein-coupled receptors (GPCRs) and regulated by calcium/calmodulin, playing a vital role in generating cyclic AMP (cAMP), a second messenger critical for signal transduction. ADCY1 is essential for synaptic plasticity, learning, and memory processes. Dysregulation of ADCY1 has been linked to neurological disorders, such as cognitive impairments and epilepsy, due to impaired cAMP signaling pathways. Its expression and activity are crucial for calcium-dependent cAMP production in neurons.
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