Human Acyl-CoA Thioesterase 7 (ACOT7) Protein
234€ (5 µg)
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935106861
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name
Human Acyl-CoA Thioesterase 7 (ACOT7) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073258
tested applications
SDS-PAGE
Description
ACOT7 is a recombinant enzyme.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Acyl-CoA Thioesterase 7 (ACOT7) |
| Host | E. coli |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O00154 |
| Alias | ACT,ACH1,BACH,LACH,LACH1,hBACH,CTE-II |
| Background | Protein ACOT7 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ACOT7, also known as brain acyl-CoA hydrolase, is a cytosolic enzyme that hydrolyzes medium- and long-chain acyl-CoA esters, influencing lipid metabolism and cellular energy dynamics. It is highly expressed in the brain and testis, where it plays a role in modulating lipid signaling molecules, such as arachidonic acid and its derivatives, which are critical for neuronal function and inflammation. ACOT7 regulates the intracellular availability of free fatty acids and CoA, impacting processes like membrane synthesis, signaling, and energy production. In the nervous system, it is involved in neuroprotection and the regulation of synaptic function. Dysregulation of ACOT7 has been linked to neuroinflammatory disorders, such as multiple sclerosis, and metabolic diseases that involve disrupted fatty acid signaling. Its tissue-specific functions highlight its importance in maintaining both neuronal and systemic lipid homeostasis.
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