Acyl-CoA Thioesterase 7 (ACOT7) Antibody
637€ (100 µl)
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935106861
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name
Acyl-CoA Thioesterase 7 (ACOT7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx110802
tested applications
ELISA, WB, IHC
Description
Acyl-Coa Thioesterase 7 Antibody is a Rabbit Polyclonal antibody against Acyl-Coa Thioesterase 7.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-CoA Thioesterase 7 (ACOT7) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O00154 |
| Gene ID | 11332 |
| NCBI Accession | NP_009205.3, NM_007274.3, NP_863654.1, NM_181864.2 |
| OMIM | 602587 |
| Alias | ACT,ACH1,BACH,LACH,LACH1,hBACH,CTE-II |
| Background | Antibody anti-ACOT7 |
| Status | RUO |
Descripción
ACOT7, also known as brain acyl-CoA hydrolase, is a cytosolic enzyme that hydrolyzes medium- and long-chain acyl-CoA esters, influencing lipid metabolism and cellular energy dynamics. It is highly expressed in the brain and testis, where it plays a role in modulating lipid signaling molecules, such as arachidonic acid and its derivatives, which are critical for neuronal function and inflammation. ACOT7 regulates the intracellular availability of free fatty acids and CoA, impacting processes like membrane synthesis, signaling, and energy production. In the nervous system, it is involved in neuroprotection and the regulation of synaptic function. Dysregulation of ACOT7 has been linked to neuroinflammatory disorders, such as multiple sclerosis, and metabolic diseases that involve disrupted fatty acid signaling. Its tissue-specific functions highlight its importance in maintaining both neuronal and systemic lipid homeostasis.
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