Human Cytosolic Acyl-Coenzyme A Thioester Hydrolase (ACOT7) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Cytosolic Acyl-Coenzyme A Thioester Hydrolase (ACOT7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385584
tested applications
ELISA
Description
Human Cytosolic Acyl-Coenzyme A Thioester Hydrolase ELISA Kit is an ELISA kit against Human Cytosolic Acyl-Coenzyme A Thioester Hydrolase (ACOT7).
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cytosolic Acyl-Coenzyme A Thioester Hydrolase |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.17 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O00154 |
| Alias | ACT,ACH1,BACH,LACH,LACH1,hBACH,CTE-II |
| Background | Elisa kits for ACOT7 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACOT7, also known as brain acyl-CoA hydrolase, is a cytosolic enzyme that hydrolyzes medium- and long-chain acyl-CoA esters, influencing lipid metabolism and cellular energy dynamics. It is highly expressed in the brain and testis, where it plays a role in modulating lipid signaling molecules, such as arachidonic acid and its derivatives, which are critical for neuronal function and inflammation. ACOT7 regulates the intracellular availability of free fatty acids and CoA, impacting processes like membrane synthesis, signaling, and energy production. In the nervous system, it is involved in neuroprotection and the regulation of synaptic function. Dysregulation of ACOT7 has been linked to neuroinflammatory disorders, such as multiple sclerosis, and metabolic diseases that involve disrupted fatty acid signaling. Its tissue-specific functions highlight its importance in maintaining both neuronal and systemic lipid homeostasis.
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