Human Acyl-CoA Thioesterase 12 (ACOT12) ELISA Kit

Name: Human Acyl-CoA Thioesterase 12 (ACOT12) ELISA Kit
Brand: Abbexa
SKU: abx385581
Price: 687.5 EUR
Availability: OnlineOnly

Este producto es parte de ACOT - Acyl-CoA Thioesterase

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits ACOT12

proveedor

Abbexa

reference

abx385581

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Acyl-CoA Thioesterase 12 (ACOT12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl-CoA Thioesterase 12 (ACOT12) concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

ACOT12 is a cytosolic enzyme that hydrolyzes short- and medium-chain acyl-CoA esters, contributing to lipid metabolism and detoxification pathways. It is expressed in tissues such as the liver, kidney, and adipose tissue, where it regulates intracellular fatty acid levels and prevents the accumulation of toxic acyl-CoA intermediates. ACOT12 plays an essential role in modulating lipid signaling molecules and providing precursors for biosynthetic pathways, including membrane lipid synthesis. Additionally, ACOT12 influences metabolic flexibility by ensuring the proper balance between fatty acid oxidation and lipid storage during fed and fasting states. Dysregulation of ACOT12 has been linked to metabolic disorders, including non-alcoholic fatty liver disease and obesity, where altered lipid metabolism affects systemic energy homeostasis. Its enzymatic activity and tissue-specific expression highlight its importance in maintaining metabolic adaptability and lipid equilibrium.

Características del producto

immunogen target

Acyl-CoA Thioesterase 12 (ACOT12)

reactivity

Human

test range

0.313 ng/ml - 20 ng/ml

sensitivity

< 0.188 ng/ml

assay type

Sandwich

assay data

Quantitative

detection method

Colorimetric

sample type

Tissue homogenates,Cell lysates,Other biological fluids

size 1

96 tests

alias

Cach,THEAL,CACH-1,STARD15

storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit

or code

ACOT12

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q8WYK0

gene id

https://www.ncbi.nlm.nih.gov/gene/134526

note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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Acyl-CoA Thioesterase 12 (ACOT12) Antibody

proveedor

Abbexa

reference

abx326772

Tested Applications

ELISA, IHC, IF/ICC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

ACOT12 Antibody is a Rabbit Polyclonal against ACOT12.

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