Human ACSS1 (Acyl-CoA synthetase short-chain family member 1) ELISA Kit

Este producto es parte de ACSS - Acyl-CoA Synthetase Short-Chain Family Member
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935106861
info@markelab.com
name
Human ACSS1 (Acyl-CoA synthetase short-chain family member 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH6093
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q9NUB1
Alias
ACAS2L,ACECS1,AceCS2L
Background
Elisa kits for ACSS1
Status
RUO

ACSS1 is a mitochondrial enzyme that activates short-chain fatty acids, primarily acetate, by converting them into acetyl-CoA, which serves as a substrate for the tricarboxylic acid (TCA) cycle, lipid synthesis, and protein acetylation. It is expressed predominantly in tissues with high metabolic demand, such as the liver, heart, and skeletal muscle, where it facilitates energy production and metabolic flexibility. ACSS1 plays a pivotal role in maintaining energy homeostasis during fasting or ketogenic states by metabolizing acetate derived from dietary sources or fatty acid oxidation. Dysregulation of ACSS1 has been linked to metabolic disorders, such as obesity and diabetes, where impaired acetate metabolism affects energy balance and lipid biosynthesis. Its role in mitochondrial acetyl-CoA production underscores its importance in supporting cellular metabolism and adapting to changes in energy availability.

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