Human ABCB1 (Multidrug resistance protein 1) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human ABCB1 (Multidrug resistance protein 1) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH2377
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P08183 |
| Alias | ABC20,CD243,CLCS,GP170,MDR1,P-GP,PGY1,p-170 |
| Background | Elisa kits for ABCB1 |
| Status | RUO |
Background
ABCB1, also known as P-glycoprotein, is a well-studied ATP-dependent efflux transporter involved in the transport of a wide range of substrates, including drugs, lipids, and xenobiotics. It is highly expressed in barrier tissues, such as the blood-brain barrier, intestines, liver, and kidneys, where it functions to protect tissues by actively exporting toxic compounds and drugs. ABCB1 plays a crucial role in pharmacokinetics, influencing drug absorption, distribution, and elimination. Overexpression of ABCB1 in cancer cells is a major contributor to multidrug resistance, as it pumps chemotherapeutic agents out of cells, reducing their efficacy. Structurally, ABCB1 contains two transmembrane domains and two ATP-binding domains, which utilize ATP hydrolysis to drive substrate transport. Its pivotal role in drug resistance and detoxification makes it a significant target in cancer therapy and pharmacological research.
Productos relacionados
ATP-Dependent Translocase ABCB1 (ABCB1) Antibody
ABCB1 Antibody is a Mouse Monoclonal against ABCB1.…
Ver producto
Human ATP-Dependent Translocase ABCB1 (ABCB1) Protein
Human ATP-Dependent Translocase ABCB1 (ABCB1) Protein is a recombinant Human protein expressed in E. coli.…
Ver producto
Mouse ATP-Dependent Translocase ABCB1 (ABCB1) Protein
Mouse ATP-Dependent Translocase ABCB1 (ABCB1) Protein is a recombinant Mouse protein expressed in E. coli.…
Ver producto