Human A Disintegrin And Metalloproteinase With Thrombospondin 19 (ADAMTS19) Protein

Este producto es parte de ADAMTS19 - ADAM metallopeptidase with thrombospondin type 1 motif 19
Product Graph
234€ (10 µg)

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935106861
info@markelab.com
name
Human A Disintegrin And Metalloproteinase With Thrombospondin 19 (ADAMTS19) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168203
tested applications
WB, SDS-PAGE

Description

ADAMTS19 Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
A Disintegrin And Metalloproteinase With Thrombospondin 19 (ADAMTS19)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 44.2 kDa  Observed MW (SDS-PAGE): 44 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Tyr325-Pro686
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
CVDP2,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 19,CVDP2,ADAMTS-19,ADAM-TS19
Background
Protein ADAMTS19
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ADAMTS19, short for A Disintegrin And Metalloproteinase with Thrombospondin Motifs 19, is a member of the ADAMTS protein family. Like other members of the ADAMTS family, ADAMTS19 contains multiple domains, including a metalloproteinase domain responsible for its proteolytic activity, as well as thrombospondin type-1 (TSP-1) motifs. ADAMTS19 is expressed in various tissues and organs, including the brain, heart, lung, and skeletal muscle, suggesting its involvement in multiple physiological processes.The precise function of ADAMTS19 is not fully understood, but it is thought to be involved in ECM remodeling, cell adhesion, and tissue development. Studies have suggested potential roles for ADAMTS19 in heart development and function, as well as in skeletal muscle biology.Mutations or dysregulation of ADAMTS19 have been implicated in several diseases and disorders. For example, mutations in the ADAMTS19 gene have been linked to a rare genetic disorder known as geleophysic dysplasia. This condition is characterized by short stature, distinctive facial features, joint stiffness, and other skeletal abnormalities.
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