G Protein Coupled Receptor 83 (GPR83) Antibody

Background

GPR83 is a G protein-coupled receptor that is widely expressed in various tissues, including the brain, immune cells, and endocrine tissues. The receptor is believed to play a role in regulating immune function, neuronal activity, and hormone secretion. GPR83 is activated by endogenous peptides, although the specific ligand(s) for GPR83 remain to be fully characterized. The receptor has been implicated in the regulation of metabolic processes, immune responses, and stress-related behaviors. In the immune system, GPR83 is thought to influence the differentiation and activity of T cells, particularly in the regulation of inflammation. In the brain, GPR83 may modulate mood and behavioral responses to stress. Dysregulation of GPR83 signaling has been associated with conditions such as autoimmune diseases, metabolic disorders, and mood disorders. As such, GPR83 is being investigated as a potential therapeutic target for treatments aimed at immune modulation, stress response, and psychiatric conditions.