GPR83 antibody
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935106861
info@markelab.com
name
GPR83 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03611
tested applications
ELISA, WB
Description
Orphan receptor. Could be a neuropeptide Y receptor.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | G protein-coupled receptor 83 (GPR83) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 48-55kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NYM4 |
| Gene ID | 10888 |
| Alias | GPR83,GIR,GPR72,glucocorticoid induced receptor,G protein-coupled receptor 72,JP05 |
| Background | Antibody anti-GPR83 |
| Status | RUO |
| Note | Mol. Weight 48-55 kDa |
Descripción
GPR83 is a G protein-coupled receptor that is widely expressed in various tissues, including the brain, immune cells, and endocrine tissues. The receptor is believed to play a role in regulating immune function, neuronal activity, and hormone secretion. GPR83 is activated by endogenous peptides, although the specific ligand(s) for GPR83 remain to be fully characterized. The receptor has been implicated in the regulation of metabolic processes, immune responses, and stress-related behaviors. In the immune system, GPR83 is thought to influence the differentiation and activity of T cells, particularly in the regulation of inflammation. In the brain, GPR83 may modulate mood and behavioral responses to stress. Dysregulation of GPR83 signaling has been associated with conditions such as autoimmune diseases, metabolic disorders, and mood disorders. As such, GPR83 is being investigated as a potential therapeutic target for treatments aimed at immune modulation, stress response, and psychiatric conditions.
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