Fibroblast Growth Factor-basic Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Fibroblast Growth Factor-basic Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx263178
Tested Applications
SDS-PAGE
Description
Fibroblast Growth Factor-basic (147 a.a) Protein is a recombinant cytokine.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | FGF 2 (147 a.a.) |
| Host | E. coli |
| Assay Type | Biological Activity: The ED was calculated by dose-dependent proliferation of mouse BALB/c 3T3 cells and was determined to be 22.5 pg/ml, corresponding to a specific activity of 4.4 × 107 units/mg. Sequence Fragment: 147 AA. |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | 16.5 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by proprietary chromatographic techniques. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: 10 mM sodium phosphate, 75 mM sodium chloride, pH 7.5. |
| Availability | Shipped within 5-10 working days. |
| Storage | The lyophilized form is stable at room temperature for up to 3 weeks. It is recommended to store this product lyophilized and desiccated at -18°C or lower. After reconstitution, store at 4°C for up to 7 days, or at or below -18°C for long-term storage. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P09038 |
| Alias | FGF-2,Basic fibroblast growth factor,Bfgf,Heparin-binding growth factor 2 (HBGF-2),FGFB |
| Background | Protein FGF2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile 18MΩ-cm H2O to a concentration of at least 100 µg/ml. |
Background
FGF2, also referred to as basic fibroblast growth factor (bFGF), is a growth factor involved in critical cellular processes, including angiogenesis, wound healing, and tissue repair It binds to FGF receptors (FGFRs) and activates pathways like Ras/MAPK and PI3K/AKT, which regulate cell proliferation, survival, and differentiation FGF2 is expressed in endothelial cells, fibroblasts, and smooth muscle cells, where it drives vascularization during tissue repair and development It promotes stem cell maintenance and supports neurogenesis by enhancing neuronal survival and regeneration Dysregulated FGF2 contributes to tumor growth, angiogenesis, and metastasis in cancers such as breast cancer and glioblastoma Targeting FGF2 signaling is a therapeutic strategy in cancer treatment, tissue regeneration, and ischemic conditions
Productos relacionados
Fibroblast Growth Factor 2 (FGF2) Antibody
Fibroblast Growth Factor 2 (FGF2) Antibody is a Rabbit Polyclonal antibody against Fibroblast Growth Factor 2 (FGF2). Th…
Ver producto
Fibroblast Growth Factor 2 (FGF2) Antibody
FGF2 is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogen…
Ver producto
Fibroblast Growth Factor 2 (FGF2) Antibody
This product is currently in development. The lead time for this product may be several months. Please contact us at…
Ver producto