Fc receptor-like protein 5 (FCRL5) Antibody (FITC)

260€ (50 µl)
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935106861
info@markelab.com
name
Fc receptor-like protein 5 (FCRL5) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx348577
Description
Fc receptor-like protein 5 (FCRL5) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human FCRL5.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | Fc receptor-like protein 5 (FCRL5)  | 
| Host | Rabbit  | 
| Reactivity | Human  | 
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user.  | 
| Clonality | Polyclonal  | 
| Conjugation | FITC  | 
| Isotype | IgG  | 
| Purity | > 95%  | 
| Purification | Purified by Protein G chromatography.  | 
| Size 1 | 50 µl  | 
| Size 2 | 100 µl  | 
| Size 3 | 200 µl  | 
| Size 4 | 1 ml  | 
| Form | Liquid  | 
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.  | 
| Availability | Shipped within 5-10 working days.  | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | Q96RD9  | 
| Gene ID | 83416, 329693  | 
| Alias | Fc receptor-like protein 5,CD307,FCRH5,IRTA2,BXMAS1,CD307e,PRO820,FcR-like protein 5,FcRL5,Fc receptor homolog 5  | 
| Background | Antibody anti-FCRL5  | 
| Status | RUO  | 
Descripción
Fc Receptor Like 5 (FCRL5) is broadly expressed on B cells, including plasma cells, and is a key regulator of B cell activation and differentiation. FCRL5 has a unique extracellular domain capable of binding to IgG antibodies, modulating immune signaling pathways. It also contains ITIM motifs and immunoreceptor tyrosine-based switch motifs (ITSMs), enabling it to integrate activating and inhibitory signals. FCRL5 expression is increased in certain B cell malignancies, such as multiple myeloma, where it may serve as a diagnostic marker or therapeutic target.
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