Fc Receptor-Like Protein 5 (FCRL5) Antibody

Name: Fc Receptor-Like Protein 5 (FCRL5) Antibody
Brand: Abbexa
SKU: abx028752
Price: 250 EUR
Availability: OnlineOnly

Este producto es parte de FCRL - Fc receptor like

Pida mas información

935106861

info@markelab.com

Precio

250€ (80 µl)

Antibody anti-FCRL5

proveedor

Abbexa

reference

abx028752

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

FCRL5 is a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Background

Fc Receptor Like 5 (FCRL5) is broadly expressed on B cells, including plasma cells, and is a key regulator of B cell activation and differentiation. FCRL5 has a unique extracellular domain capable of binding to IgG antibodies, modulating immune signaling pathways. It also contains ITIM motifs and immunoreceptor tyrosine-based switch motifs (ITSMs), enabling it to integrate activating and inhibitory signals. FCRL5 expression is increased in certain B cell malignancies, such as multiple myeloma, where it may serve as a diagnostic marker or therapeutic target.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Fc Receptor-Like Protein 5 (FCRL5)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified through a protein A column, followed by peptide affinity purification.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

FCRL5

dry ice

availability

Shipped within 5-10 working days.

alias

Fc receptor-like protein 5,CD307,FCRH5,IRTA2,BXMAS1,CD307e,PRO820,FcR-like protein 5,FcRL5,Fc receptor homolog 5

uniprot id

https://www.uniprot.org/uniprotkb/Q96RD9

note

This product is for research use only.

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