Fc Receptor-Like Protein 5 (FCRL5) Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Fc Receptor-Like Protein 5 (FCRL5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037099
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the FCRL5 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fc Receptor-Like Protein 5 (FCRL5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Fc receptor-like protein 5,CD307,FCRH5,IRTA2,BXMAS1,CD307e,PRO820,FcR-like protein 5,FcRL5,Fc receptor homolog 5 |
| Background | Antibody anti-FCRL5 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Fc Receptor Like 5 (FCRL5) is broadly expressed on B cells, including plasma cells, and is a key regulator of B cell activation and differentiation. FCRL5 has a unique extracellular domain capable of binding to IgG antibodies, modulating immune signaling pathways. It also contains ITIM motifs and immunoreceptor tyrosine-based switch motifs (ITSMs), enabling it to integrate activating and inhibitory signals. FCRL5 expression is increased in certain B cell malignancies, such as multiple myeloma, where it may serve as a diagnostic marker or therapeutic target.
Related Products
Fc Receptor-Like Protein 5 (FCRL5) Antibody
Rabbit polyclonal antibody against FCRL5 protein. Immunogen region is Internal.
Ver Producto
Fc Receptor-Like Protein 5 (FCRL5) Antibody
FCRL5 is a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Ver Producto