Fc receptor-like protein 5 (FCRL5) Antibody (Biotin)
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Fc receptor-like protein 5 (FCRL5) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx348578
tested applications
ELISA
Description
Fc receptor-like protein 5 (FCRL5) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human FCRL5.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fc receptor-like protein 5 (FCRL5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96RD9 |
| Gene ID | 83416, 329693 |
| Alias | Fc receptor-like protein 5,CD307,FCRH5,IRTA2,BXMAS1,CD307e,PRO820,FcR-like protein 5,FcRL5,Fc receptor homolog 5 |
| Background | Antibody anti-FCRL5 |
| Status | RUO |
Descripción
Fc Receptor Like 5 (FCRL5) is broadly expressed on B cells, including plasma cells, and is a key regulator of B cell activation and differentiation. FCRL5 has a unique extracellular domain capable of binding to IgG antibodies, modulating immune signaling pathways. It also contains ITIM motifs and immunoreceptor tyrosine-based switch motifs (ITSMs), enabling it to integrate activating and inhibitory signals. FCRL5 expression is increased in certain B cell malignancies, such as multiple myeloma, where it may serve as a diagnostic marker or therapeutic target.
Related Products
Fc Receptor-Like Protein 5 (FCRL5) Antibody
Rabbit polyclonal antibody against FCRL5 protein. Immunogen region is Internal.
Ver Producto
Fc Receptor-Like Protein 5 (FCRL5) Antibody
FCRL5 is a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Ver Producto