Fc Receptor-Like Protein 2 (FCRL2) Antibody
312€ (0.1 mg)
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935106861
info@markelab.com
name
Fc Receptor-Like Protein 2 (FCRL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx347159
tested applications
FCM
Description
Fc Receptor-Like Protein 2 (FCRL2) Antibody is a Mouse Monoclonal Antibody against Fc Receptor-Like Protein 2 (FCRL2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fc Receptor-Like Protein 2 (FCRL2) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-4 μg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone ID | Y255 |
| Purification | Purified by Protein A affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | PBS, pH 7.4, 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q96LA5 |
| Gene ID | 79368 |
| Alias | Fc receptor-like protein 2,FCRH2,IFGP4,IRTA4,SPAP1,CD307b,SPAP1A,SPAP1B,SPAP1C,FcR-like protein 2,FcRL2,IFGP family protein 4 |
| Background | Antibody anti-FCRL2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Fc Receptor Like 2 (FCRL2) is another member of the FCRL family, predominantly expressed on mature B cells and plasma cells. FCRL2 also contains cytoplasmic ITIM motifs, indicating its role as an inhibitory receptor. It is involved in modulating B cell receptor (BCR) signaling, plasma cell survival, and antibody production. Alterations in FCRL2 expression have been implicated in hematological malignancies such as chronic lymphocytic leukemia (CLL), where it may serve as a biomarker for disease progression and therapeutic targeting.
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