Fc Receptor-Like Protein 2 (FCRL2) Antibody
169€ (20 µl)
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935106861
info@markelab.com
name
Fc Receptor-Like Protein 2 (FCRL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx322029
tested applications
ELISA, WB, IHC
Description
FCRL2 Antibody is a Rabbit Polyclonal against FCRL2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fc Receptor-Like Protein 2 (FCRL2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LA5 |
| Gene ID | 79368 |
| NCBI Accession | NP_001152960.1, NM_001159488.1, NP_110391.2, NM_030764.3 |
| OMIM | 606509 |
| Alias | Fc receptor-like protein 2,FCRH2,IFGP4,IRTA4,SPAP1,CD307b,SPAP1A,SPAP1B,SPAP1C,FcR-like protein 2,FcRL2,IFGP family protein 4 |
| Background | Antibody anti-FCRL2 |
| Status | RUO |
Descripción
Fc Receptor Like 2 (FCRL2) is another member of the FCRL family, predominantly expressed on mature B cells and plasma cells. FCRL2 also contains cytoplasmic ITIM motifs, indicating its role as an inhibitory receptor. It is involved in modulating B cell receptor (BCR) signaling, plasma cell survival, and antibody production. Alterations in FCRL2 expression have been implicated in hematological malignancies such as chronic lymphocytic leukemia (CLL), where it may serve as a biomarker for disease progression and therapeutic targeting.
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