EGF-Like Module Receptor 3 (EMR3) Antibody
351€ (100 µg)
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935106861
info@markelab.com
name
EGF-Like Module Receptor 3 (EMR3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx414254
tested applications
FCM, IP
Description
EGF-Like Module Receptor 3 (EMR3) Antibody is a Hamster Monoclonal antibody against EGF-Like Module Receptor 3 (EMR3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | EGF-Like Module Receptor 3 (EMR3) |
| Host | Hamster |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM, IP |
| Buffer | PBS. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BY15 |
| Alias | ADGRE3,EMR3 (EGF-like module-containing, mucin-like, hormone receptor-like 3 |
| Background | Antibody anti-ADGRE3 |
| Status | RUO |
| Note | Concentration: 1.0 mg/ml - |
Descripción
ADGRE3, also known as EMR3, is a member of the adhesion GPCR family expressed mainly in myeloid and granulocytic cells. It is believed to contribute to immune regulation and cellular communication in the innate immune system, although its precise biological functions remain less well-defined compared to ADGRE1 and ADGRE2. ADGRE3 contains extracellular EGF-like domains, characteristic of this receptor family, which mediate interactions with the extracellular environment and other immune cells. It is thought to play a role in modulating inflammatory responses and potentially in tumor-associated immune processes. Dysregulation of ADGRE3 has been implicated in certain cancers and inflammatory conditions, suggesting its involvement in immune cell signaling and tissue remodeling.
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