Adhesion G Protein-Coupled Receptor E3 (ADGRE3) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor E3 (ADGRE3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx324103
tested applications
ELISA, WB, IF/ICC
Description
EMR3 Antibody is a Rabbit Polyclonal against EMR3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor E3 (ADGRE3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BY15 |
| Gene ID | 84658 |
| Alias | ADGRE3,EMR3 (EGF-like module-containing, mucin-like, hormone receptor-like 3 |
| Background | Antibody anti-ADGRE3 |
| Status | RUO |
Descripción
ADGRE3, also known as EMR3, is a member of the adhesion GPCR family expressed mainly in myeloid and granulocytic cells. It is believed to contribute to immune regulation and cellular communication in the innate immune system, although its precise biological functions remain less well-defined compared to ADGRE1 and ADGRE2. ADGRE3 contains extracellular EGF-like domains, characteristic of this receptor family, which mediate interactions with the extracellular environment and other immune cells. It is thought to play a role in modulating inflammatory responses and potentially in tumor-associated immune processes. Dysregulation of ADGRE3 has been implicated in certain cancers and inflammatory conditions, suggesting its involvement in immune cell signaling and tissue remodeling.
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