EGF-Like Module Receptor 3 (EMR3) Antibody

Este producto es parte de ADGRE - Adhesion G protein-coupled receptor E
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52€ (10 µg)

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935106861
info@markelab.com
name
EGF-Like Module Receptor 3 (EMR3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015238
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against EMR3 protein. Immunogen region is C-terminal.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetEGF-Like Module Receptor 3 (EMR3)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 110 µg
Size 2100 µg
Size 3200 µg
Size 4300 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9BY15
AliasADGRE3,EMR3 (EGF-like module-containing, mucin-like, hormone receptor-like 3
BackgroundAntibody anti-ADGRE3
StatusRUO
NoteConcentration: 1 mg/ml -

Descripción

ADGRE3, also known as EMR3, is a member of the adhesion GPCR family expressed mainly in myeloid and granulocytic cells. It is believed to contribute to immune regulation and cellular communication in the innate immune system, although its precise biological functions remain less well-defined compared to ADGRE1 and ADGRE2. ADGRE3 contains extracellular EGF-like domains, characteristic of this receptor family, which mediate interactions with the extracellular environment and other immune cells. It is thought to play a role in modulating inflammatory responses and potentially in tumor-associated immune processes. Dysregulation of ADGRE3 has been implicated in certain cancers and inflammatory conditions, suggesting its involvement in immune cell signaling and tissue remodeling.

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