EGF-Like Module Receptor 3 (EMR3) Antibody

Este producto es parte de ADGRE - Adhesion G protein-coupled receptor E
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52€ (10 µg)

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935106861
info@markelab.com
name
EGF-Like Module Receptor 3 (EMR3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015238
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against EMR3 protein. Immunogen region is C-terminal.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
EGF-Like Module Receptor 3 (EMR3)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9BY15
Alias
ADGRE3,EMR3 (EGF-like module-containing, mucin-like, hormone receptor-like 3
Background
Antibody anti-ADGRE3
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

ADGRE3, also known as EMR3, is a member of the adhesion GPCR family expressed mainly in myeloid and granulocytic cells. It is believed to contribute to immune regulation and cellular communication in the innate immune system, although its precise biological functions remain less well-defined compared to ADGRE1 and ADGRE2. ADGRE3 contains extracellular EGF-like domains, characteristic of this receptor family, which mediate interactions with the extracellular environment and other immune cells. It is thought to play a role in modulating inflammatory responses and potentially in tumor-associated immune processes. Dysregulation of ADGRE3 has been implicated in certain cancers and inflammatory conditions, suggesting its involvement in immune cell signaling and tissue remodeling.

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