Butyrophilin-Like Protein 8 (BTNL8) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Butyrophilin-Like Protein 8 (BTNL8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230986
tested applications
ELISA, WB
Description
BTNL8 Antibody is a Rabbit Polyclonal against BTNL8.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Butyrophilin-Like Protein 8 (BTNL8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6UX41 |
| Gene ID | 79908 |
| OMIM | 615606 |
| Alias | BTN9.2,Butyrophilin-like protein 8 |
| Background | Antibody anti-BTNL8 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Butyrophilin like 8 (BTNL8) is a member of the butyrophilin-like family within the immunoglobulin superfamily, primarily expressed in epithelial tissues where it is believed to play a role in immune regulation. This protein shares structural similarities with other butyrophilins known to regulate γδ T cell activation, which is critical for maintaining tissue homeostasis and surveillance against infections and malignancies. BTNL8 is thought to contribute to modulating immune responses at barrier sites, including the skin and mucosal surfaces, where it may interact with local immune cells. Emerging studies suggest that BTNL8 could influence inflammation and autoimmune pathways, though its specific interactions and molecular mechanisms remain under investigation. Its potential involvement in maintaining epithelial integrity and modulating immune responses makes it an area of interest for research into inflammatory disorders and epithelial cancers.
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