Butyrophilin-Like Protein 8 (BTNL8) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Butyrophilin-Like Protein 8 (BTNL8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122174
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the BTNL8 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Butyrophilin-Like Protein 8 (BTNL8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC119696 |
| Alias | BTN9.2,Butyrophilin-like protein 8 |
| Background | Antibody anti-BTNL8 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Butyrophilin like 8 (BTNL8) is a member of the butyrophilin-like family within the immunoglobulin superfamily, primarily expressed in epithelial tissues where it is believed to play a role in immune regulation. This protein shares structural similarities with other butyrophilins known to regulate γδ T cell activation, which is critical for maintaining tissue homeostasis and surveillance against infections and malignancies. BTNL8 is thought to contribute to modulating immune responses at barrier sites, including the skin and mucosal surfaces, where it may interact with local immune cells. Emerging studies suggest that BTNL8 could influence inflammation and autoimmune pathways, though its specific interactions and molecular mechanisms remain under investigation. Its potential involvement in maintaining epithelial integrity and modulating immune responses makes it an area of interest for research into inflammatory disorders and epithelial cancers.
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