Butyrophilin-Like Protein 8 (BTNL8) Antibody
292.5€ (80 µl)
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Name
Butyrophilin-Like Protein 8 (BTNL8) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx032380
Tested Applications
ELISA, WB, FCM
Description
BTNL8 Antibody is a Rabbit Polyclonal antibody against BTNL8.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Butyrophilin-Like Protein 8 (BTNL8) Immunogen: KLH-conjugated synthetic peptide between 257-285 amino acids from the Central region of human BTNL8. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 56.7 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6UX41 |
| Alias | BTN9.2,Butyrophilin-like protein 8 |
| Background | Antibody anti-BTNL8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Butyrophilin like 8 (BTNL8) is a member of the butyrophilin-like family within the immunoglobulin superfamily, primarily expressed in epithelial tissues where it is believed to play a role in immune regulation. This protein shares structural similarities with other butyrophilins known to regulate γδ T cell activation, which is critical for maintaining tissue homeostasis and surveillance against infections and malignancies. BTNL8 is thought to contribute to modulating immune responses at barrier sites, including the skin and mucosal surfaces, where it may interact with local immune cells. Emerging studies suggest that BTNL8 could influence inflammation and autoimmune pathways, though its specific interactions and molecular mechanisms remain under investigation. Its potential involvement in maintaining epithelial integrity and modulating immune responses makes it an area of interest for research into inflammatory disorders and epithelial cancers.
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