BTNL8 antibody
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935106861
info@markelab.com
name
BTNL8 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00986
tested applications
ELISA, WB
Description
May stimulate primary immune response. Acts on T-cell stimulated sub-optimally through the TCR/CD3 complex stimulating their proliferation and cytokine production.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | butyrophilin-like 8 (BTNL8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q6UX41 |
| Gene ID | 79908 |
| Alias | BTN9.2,Butyrophilin-like protein 8 |
| Background | Antibody anti-BTNL8 |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
Descripción
Butyrophilin like 8 (BTNL8) is a member of the butyrophilin-like family within the immunoglobulin superfamily, primarily expressed in epithelial tissues where it is believed to play a role in immune regulation. This protein shares structural similarities with other butyrophilins known to regulate γδ T cell activation, which is critical for maintaining tissue homeostasis and surveillance against infections and malignancies. BTNL8 is thought to contribute to modulating immune responses at barrier sites, including the skin and mucosal surfaces, where it may interact with local immune cells. Emerging studies suggest that BTNL8 could influence inflammation and autoimmune pathways, though its specific interactions and molecular mechanisms remain under investigation. Its potential involvement in maintaining epithelial integrity and modulating immune responses makes it an area of interest for research into inflammatory disorders and epithelial cancers.
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