Bone Marrow Stromal Cell Antigen 2 (BST2) Antibody

Este producto es parte de BST2 - bone marrow stromal cell antigen 2
Product Graph
273€ (100 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Bone Marrow Stromal Cell Antigen 2 (BST2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx175579
tested applications
WB, IHC, IF/ICC

Description

Bone Marrow Stromal Cell Antigen 2 (BST2) Antibody is a Rabbit Polyclonal antibody against Bone Marrow Stromal Cell Antigen 2 (BST2).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Bone Marrow Stromal Cell Antigen 2 (BST2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
CD317,HM1.24,TETHERIN,HM1.24 antigen
Background
Antibody anti-BST2
Status
RUO

Descripción

Related Products

FNab00970

anti- BST2 antibody

IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted. Its target viruses belong to diverse families, including retroviridae: human immunodeficiency virus type 1(HIV-1), human immunodeficiency virus type 2(HIV-2), simian immunodeficiency viruses(SIVs), equine infectious anemia virus(EIAV), feline immunodeficiency virus(FIV), prototype foamy virus(PFV), Mason-Pfizer monkey virus(MPMV), human T-cell leukemia virus type 1(HTLV-1), Rous sarcoma virus(RSV) and murine leukemia virus(MLV), flavivirideae: hepatitis C virus(HCV), filoviridae: ebola virus(EBOV) and marburg virus(MARV), arenaviridae: lassa virus(LASV) and machupo virus(MACV), herpesviridae: kaposis sarcoma-associated herpesvirus(KSHV), rhabdoviridae: vesicular stomatitis virus(VSV), orthomyxoviridae: influenza A virus, and paramyxoviridae: nipah virus. Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration. Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection. Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. Isoform 1 and isoform 2 are both effective viral restriction factors but have differing antiviral and signaling activities. Isoform 2 is resistant to HIV-1 Vpu-mediated degradation and restricts HIV-1 viral budding in the presence of Vpu. Isoform 1 acts as an activator of NF-kappa-B and this activity is inhibited by isoform 2.

Ver Producto
Pr22815

Recombinant Human BST2

Ver Producto
abx001564

Bone Marrow Stromal Antigen 2 (BST2) Antibody

BST2 Antibody is a Rabbit Polyclonal antibody against BST2. Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.

Ver Producto