ATP Binding Cassette Subfamily E Member 1 (ABCE1) Antibody
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Description
Rabbit Polyclonal against the ABCE1 protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATP Binding Cassette Subfamily E Member 1 (ABCE1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_001040876 |
| Alias | ABC38,OABP,RLI,RLI1,RNASEL1 |
| Background | Antibody anti-ABCE1 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ABCE1, also known as the ATP-binding cassette protein E1 or RNase L inhibitor (RLI), is a unique member of the ATP-binding cassette (ABC) transporter superfamily. Unlike most ABC transporters, which are involved in the translocation of various substrates across membranes, ABCE1 primarily functions in the regulation of RNA processing and translation. It is highly conserved across different species, highlighting its fundamental biological importance.ABCE1 works by inhibiting the activity of ribonuclease L, thereby opposing the antiviral properties of ribonuclease L and enabling the virus to synthesize viral proteins. Additionally, ABCE1 has been implicated in influencing tumor cell proliferation
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