anti- WASF4-Specific antibody

Este producto es parte de WASF - WASP family member
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935106861
info@markelab.com
name
anti- WASF4-Specific antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09469
tested applications
ELISA, WB, IF

Description

WASF4, also named as SCAR2, belongs to the SCAR/WAVE family. WASF4 is a downstream effector molecule which involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. The antibody is specific to WASF4.

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Product specifications

CategoryPrimary Antibodies
Immunogen TargetWAS protein family, member 4
HostRabbit
Reactivityhuman,mouse
Recommended DilutionWB: 1:500-1:5000;IF: 1:10-1:100
Clonalitypolyclonal
ConjugationUnconjugated
IsotypeIgG
Observed MW68 kDa
Purity≥95% as determined by SDS-PAGE
PurificationImmunogen affinity purified
Size 1100µg
Formliquid
Tested ApplicationsELISA, WB, IF
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt IDQ8IV90
AliasWASF4
BackgroundAntibody anti-WASF4P
StatusRUO
NoteThis product is for research use only.

Descripción

WASP family member 4, pseudogene (WASF4P) is a pseudogene related to the WASP family, which regulates actin cytoskeleton dynamics, cell movement, and immune responses in various cell types Despite being classified as a pseudogene, WASF4P shares functional similarities with its active counterparts, such as WASF1 and WASF2, in the regulation of cellular structures like lamellipodia and filopodia These actin-rich structures are essential for cell migration and morphogenesis in tissues like the immune system and the developing nervous system Although its functional contribution remains unclear, WASF4P may have some role in cellular processes that warrant further investigation, particularly in cases of alternative splicing or mutations that lead to alterations in its expression It could potentially influence cellular responses to external stimuli or injury, especially in actin dynamics, although its full biological significance has yet to be fully explored in comparison to other WASP family proteins

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