Recombinant Human WASH complex subunit 4

Background

WASP family member 4, pseudogene (WASF4P) is a pseudogene related to the WASP family, which regulates actin cytoskeleton dynamics, cell movement, and immune responses in various cell types Despite being classified as a pseudogene, WASF4P shares functional similarities with its active counterparts, such as WASF1 and WASF2, in the regulation of cellular structures like lamellipodia and filopodia These actin-rich structures are essential for cell migration and morphogenesis in tissues like the immune system and the developing nervous system Although its functional contribution remains unclear, WASF4P may have some role in cellular processes that warrant further investigation, particularly in cases of alternative splicing or mutations that lead to alterations in its expression It could potentially influence cellular responses to external stimuli or injury, especially in actin dynamics, although its full biological significance has yet to be fully explored in comparison to other WASP family proteins