The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
Primary Antibodies
polyclonal
human,mouse,rat
RAB43, member RAS oncogene family
Rabbit
IgG
Unconjugated
liquid
ELISA, WB
23 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
RAB43
Ras-related protein Rab-41,Ras-related protein Rab-43,RAB41
This product is for research use only.
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles...
Precio a consultar
Ver másRas-Related Protein Rab-43 Antibody is a Rabbit Polyclonal antibody against Ras-Related Protein Rab-43.
612.5€ (100 µl)
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