Ras-Related Protein Rab-43 (RAB43) Antibody
357.5€ (100 µg)
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Name
Ras-Related Protein Rab-43 (RAB43) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx145877
Tested Applications
ELISA, WB, IHC
Description
RAB43 Antibody is a Rabbit Polyclonal against RAB43.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Related Protein Rab-43 (RAB43) Immunogen: A peptide corresponding to N-terminal region of human RAB43 protein. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 23 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q86YS6 |
| Gene ID | 339122 |
| Alias | Ras-related protein Rab-41,Ras-related protein Rab-43,RAB41 |
| Background | Antibody anti-RAB43 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB43, member RAS oncogene family (RAB43) is a member of the RAB family of small GTPases that plays a critical role in regulating vesicle trafficking within the cell. RAB43 is involved in the transport of vesicles between the Golgi apparatus and the endosomal system, helping to mediate protein sorting and trafficking processes essential for cellular homeostasis. This protein is particularly important for regulating the recycling and degradation of membrane proteins, which affects cellular communication and signaling. RAB43 is also implicated in the regulation of receptor endocytosis, a process that is vital for maintaining the responsiveness of cells to external stimuli. In neurons, RAB43 contributes to the movement of synaptic vesicles, ensuring the proper release and recycling of neurotransmitters. Given its role in vesicular transport, RAB43 has been linked to a variety of diseases, including cancer, where disruptions in vesicle trafficking can lead to alterations in receptor signaling pathways and contribute to tumor progression. Additionally, RAB43's involvement in cellular stress responses suggests that it may also be important in protecting cells against oxidative stress and other forms of damage, thereby playing a protective role in several degenerative diseases.
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