RAB34 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
RAB34 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07018
tested applications
ELISA, WB, IHC
Description
Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region(By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB34, member RAS oncogene family (RAB34) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:10000; IP: 1:200-1:2000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 29 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BZG1 |
| Gene ID | 83871 |
| Alias | RAH,NARR,OFD20,RAB39,Nine amino-acid residue-repeats,Ras-related protein Rab-34, isoform NARR |
| Background | Antibody anti-RAB34 |
| Status | RUO |
| Note | Mol. Weight 29 kDa |
Descripción
RAB34, member RAS oncogene family (RAB34) is involved in regulating intracellular vesicular trafficking, particularly in the movement of vesicles between the endosomes and other cellular compartments It plays a crucial role in the endocytic and exocytic pathways by mediating the transport of cargo proteins to the plasma membrane or to lysosomes for degradation RAB34 has been implicated in autophagy, a vital process for maintaining cellular homeostasis by degrading and recycling damaged cellular components Additionally, RAB34 is involved in controlling the dynamics of the Golgi apparatus and the vesicular trafficking from this organelle, ensuring proper protein sorting and trafficking RAB34 also has roles in regulating the immune response and cellular signaling through its effects on vesicular fusion and the recycling of signaling receptors Dysregulation of RAB34 has been linked to neurodegenerative diseases, cancer, and immune-related disorders where altered vesicular trafficking and membrane dynamics contribute to pathological changes in cellular function and tissue homeostasis
Related Products
RAB34 antibody
Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region(By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
Ver Producto
RAB34, Member RAS Oncogene Family (RAB34) Antibody
Rabbit polyclonal antibody against RAB34 protein. Immunogen region is C-terminal.
Ver Producto
Rab34, Member Ras Oncogene Family (RAB34) Antibody
Rab34, Member Ras Oncogene Family Antibody is a Rabbit Polyclonal antibody against Rab34, Member Ras Oncogene Family.
Ver Producto