RAB34, Member RAS Oncogene Family (RAB34) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
RAB34, Member RAS Oncogene Family (RAB34) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014796
tested applications
ELISA, IHC
Description
Rabbit polyclonal antibody against RAB34 protein. Immunogen region is C-terminal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB34, Member RAS Oncogene Family (RAB34) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/50 - 1/100, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BZG1 |
| Alias | RAH,NARR,OFD20,RAB39,Nine amino-acid residue-repeats,Ras-related protein Rab-34, isoform NARR |
| Background | Antibody anti-RAB34 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
RAB34, member RAS oncogene family (RAB34) is involved in regulating intracellular vesicular trafficking, particularly in the movement of vesicles between the endosomes and other cellular compartments It plays a crucial role in the endocytic and exocytic pathways by mediating the transport of cargo proteins to the plasma membrane or to lysosomes for degradation RAB34 has been implicated in autophagy, a vital process for maintaining cellular homeostasis by degrading and recycling damaged cellular components Additionally, RAB34 is involved in controlling the dynamics of the Golgi apparatus and the vesicular trafficking from this organelle, ensuring proper protein sorting and trafficking RAB34 also has roles in regulating the immune response and cellular signaling through its effects on vesicular fusion and the recycling of signaling receptors Dysregulation of RAB34 has been linked to neurodegenerative diseases, cancer, and immune-related disorders where altered vesicular trafficking and membrane dynamics contribute to pathological changes in cellular function and tissue homeostasis
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