Rab34, Member Ras Oncogene Family (RAB34) Antibody
637€ (100 µl)
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Name
Rab34, Member Ras Oncogene Family (RAB34) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx114982
Tested Applications
ELISA, WB
Description
Rab34, Member Ras Oncogene Family Antibody is a Rabbit Polyclonal antibody against Rab34, Member Ras Oncogene Family.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Rab34, Member Ras Oncogene Family (RAB34) Immunogen: Human RAB34. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P0DI83 |
| Gene ID | 83871 |
| NCBI Accession | NP_001243210.1, NM_001256281.2 |
| OMIM | 61917 |
| Alias | RAH,NARR,OFD20,RAB39,Nine amino-acid residue-repeats,Ras-related protein Rab-34, isoform NARR |
| Background | Antibody anti-RAB34 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB34, member RAS oncogene family (RAB34) is involved in regulating intracellular vesicular trafficking, particularly in the movement of vesicles between the endosomes and other cellular compartments It plays a crucial role in the endocytic and exocytic pathways by mediating the transport of cargo proteins to the plasma membrane or to lysosomes for degradation RAB34 has been implicated in autophagy, a vital process for maintaining cellular homeostasis by degrading and recycling damaged cellular components Additionally, RAB34 is involved in controlling the dynamics of the Golgi apparatus and the vesicular trafficking from this organelle, ensuring proper protein sorting and trafficking RAB34 also has roles in regulating the immune response and cellular signaling through its effects on vesicular fusion and the recycling of signaling receptors Dysregulation of RAB34 has been linked to neurodegenerative diseases, cancer, and immune-related disorders where altered vesicular trafficking and membrane dynamics contribute to pathological changes in cellular function and tissue homeostasis
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