PI16 antibody
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935106861
info@markelab.com
name
PI16 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06415
tested applications
ELISA, WB
Description
Putative serine protease inhibitor.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | peptidase inhibitor 16 (PI16) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 49-60 kDa,30-35 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q6UXB8 |
| Gene ID | 221476 |
| Alias | CD364,PSPBP,CRISP9,MSMBBP,PI-16,Cysteine-rich secretory protein 9,PSP94-binding protein |
| Background | Antibody anti-PI16 |
| Status | RUO |
| Note | Mol. Weight 49-60 kDa, 30-35 kDa |
Descripción
Peptidase Inhibitor 16 (PI16), also known as PSPBP (prostate secretory protein binding protein), is a member of the peptidase inhibitor family that plays a role in regulating protease activity in various tissues, particularly in the cardiovascular, immune, and reproductive systems. PI16 is a secreted protein expressed primarily by stromal fibroblasts, prostate cells, and cardiac tissues, among others. It has been identified as an immunomodulatory molecule and a marker for fibroblasts, especially those involved in tissue remodeling processes. By modulating protease activity, PI16 indirectly influences extracellular matrix (ECM) composition and cellular signaling, contributing to processes like fibrosis, inflammation, and cardiac function. Given its tissue-specific expression and involvement in immune responses, PI16 has been the subject of studies focused on its roles in cardiovascular diseases, cancer, and immune regulation.
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