DPH1 antibody
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935106861
info@markelab.com
name
DPH1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06045
tested applications
ELISA, WB, IHC, IF
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DPH1 homolog (DPH1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 40-60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BZG8 |
| Alias | DPH2L,OVCA1,DEDSSH,DPH2L1,Diphthamide biosynthesis protein 1,Diphtheria toxin resistance protein 1,Ovarian cancer-associated gene 1 protein |
| Background | Antibody anti-DPH1 |
| Status | RUO |
| Note | Mol. Weight 40-60 kDa |
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Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM].
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