Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM].
Primary Antibodies
Polyclonal
Human
2-(3-Amino-3-Carboxypropyl)histidine Synthase Subunit 1 (DPH1)
Rabbit
Unconjugated
Liquid
ELISA, WB
Purified through a protein A column, followed by peptide affinity purification.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
DPH1
No
Shipped within 5-10 working days.
DPH2L,OVCA1,DEDSSH,DPH2L1,Diphthamide biosynthesis protein 1,Diphtheria toxin resistance protein 1,Ovarian cancer-associated gene 1 protein
This product is for research use only.
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM ...
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