anti- MYOM1-Specific antibody
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935106861
info@markelab.com
name
anti- MYOM1-Specific antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05516
tested applications
ELISA, WB, IHC
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | myomesin 1, 185kDa |
| Host | Rabbit |
| Reactivity | human,mouse,rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 190kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P52179 |
| Alias | SKELEMIN,Myomesin family member 1,190 kDa titin-associated protein,190 kDa connectin-associated protein |
| Background | Antibody anti-MYOM1 |
| Status | RUO |
| Note | This product is for research use only. |
Myomesin 1 (MYOM1) is a key structural protein located within the M-band of sarcomeres, the fundamental contractile units in muscle fibers. It serves as an essential linker between the thick myosin filaments, stabilizing the sarcomeric architecture during muscle contraction and relaxation cycles. MYOM1 plays a significant role in maintaining mechanical stability and transmitting forces generated within the sarcomere. Additionally, it interacts with other M-band proteins such as myosin-binding proteins and titin, facilitating the alignment and integrity of muscle filaments. Mutations or dysregulation in MYOM1 have been associated with muscle disorders, highlighting its critical role in both skeletal and cardiac muscle function.
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