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This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Primary Antibodies
polyclonal
human,mouse,rat
Insulin receptor substrate 2 peptied
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC
170 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
IRS2
IRS2, IRS-2, insulin receptor substrate 2
This product is for research use only.
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Ver másThis gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, i...
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