The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Primary Antibodies
polyclonal
human,mouse,rat
FGF2
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
FGF2
FGF-2,Basic fibroblast growth factor,Bfgf,Heparin-binding growth factor 2 (HBGF-2),FGFB
This product is for research use only.
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Ver másThe protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind hepar...
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