anti- CORO1C antibody

Este producto es parte de CORO - Coronin
anti- CORO1C antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-CORO1C

proveedor

FineTest

reference

FNab01883

Tested Applications

ELISA, WB, IHC, IF, IP

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

May be involved in cytokinesis, motility, and signal transduction. Isoform 3: Involved in myogenic differentiation.


Background

Coronin 1C (CORO1C) is another member of the coronin protein family with a role in regulating actin filament dynamics. Like CORO1A and CORO1B, CORO1C plays a crucial role in cellular processes such as actin-based movement, endocytosis, and cytokinesis. However, CORO1C is particularly important in the regulation of the immune system, where it modulates the signaling pathways of immune cells, including T cells, and contributes to the response to inflammation. It is also involved in maintaining the structural integrity of immune synapses, which are crucial for the communication between immune cells. Similar to the other coronins, CORO1C's dysregulation can impair immune function and has been associated with conditions that affect immune responses. Understanding the role of CORO1C in immune cell signaling and actin dynamics is critical for advancing therapeutic strategies targeting immune-related diseases.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

coronin, actin binding protein, 1C


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IHC, IF, IP


observerd MW

57kd


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

CORO1C


alias

HCRNN4,Coronin-3,Coronin-1C,CRN2,CRNN4


note

This product is for research use only.


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