anti- CORO1C antibody
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Precio
Precio a consultar
Antibody anti-CORO1C
proveedor
FineTestreference
FNab01883Tested Applications
ELISA, WB, IHC, IF, IPreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
May be involved in cytokinesis, motility, and signal transduction. Isoform 3: Involved in myogenic differentiation.
Background
Coronin 1C (CORO1C) is another member of the coronin protein family with a role in regulating actin filament dynamics. Like CORO1A and CORO1B, CORO1C plays a crucial role in cellular processes such as actin-based movement, endocytosis, and cytokinesis. However, CORO1C is particularly important in the regulation of the immune system, where it modulates the signaling pathways of immune cells, including T cells, and contributes to the response to inflammation. It is also involved in maintaining the structural integrity of immune synapses, which are crucial for the communication between immune cells. Similar to the other coronins, CORO1C's dysregulation can impair immune function and has been associated with conditions that affect immune responses. Understanding the role of CORO1C in immune cell signaling and actin dynamics is critical for advancing therapeutic strategies targeting immune-related diseases.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
coronin, actin binding protein, 1C
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IHC, IF, IP
observerd MW
57kd
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
CORO1C
alias
HCRNN4,Coronin-3,Coronin-1C,CRN2,CRNN4
uniprot id
note
This product is for research use only.
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