Name: anti- ADCY1 antibody
Brand: FineTest
SKU: FNab00155
Availability: OnlineOnly

Descripción

Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels(By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina(By similarity).

Background

ADCY1 is a membrane-bound enzyme predominantly expressed in the brain, specifically in neuronal tissues. It is activated by G-protein-coupled receptors (GPCRs) and regulated by calcium/calmodulin, playing a vital role in generating cyclic AMP (cAMP), a second messenger critical for signal transduction. ADCY1 is essential for synaptic plasticity, learning, and memory processes. Dysregulation of ADCY1 has been linked to neurological disorders, such as cognitive impairments and epilepsy, due to impaired cAMP signaling pathways. Its expression and activity are crucial for calcium-dependent cAMP production in neurons.

Características del producto

clonality

polyclonal

reactivity

human

immunogen target

adenylate cyclase 1(brain)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB

observerd MW

123 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:200-1:2000

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ADCY1

alias

AC1,DFNB44,ATP pyrophosphate-lyase 1

uniprot id

https://www.uniprot.org/uniprotkb/Q08828

gene id

https://www.ncbi.nlm.nih.gov/gene/107

note

This product is for research use only.

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Human ADCY1(Adenylate cyclase type 1) ELISA Kit

proveedor

FineTest

reference

EH1518

reactivity

human

status

RUO

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