ABT1 antibody
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Name
ABT1 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab00056
Tested Applications
ELISA, WB, IHC
Description
Could be a novel TATA-binding protein(TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes(By similarity).
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | activator of basal transcription 1 (ABT1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 31 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9ULW3 |
| Gene ID | 29777 |
| Alias | Esf2,hABT1 |
| Background | Antibody anti-ABT1 |
| Status | RUO |
| Note | Mol. Weight 31 kDa |
Background
ABT1 (Activator of Basal Transcription 1) is a protein involved in the regulation of gene expression by facilitating the initiation of transcription. It is a component of the pre-initiation complex (PIC), which assembles at the promoter region of genes to initiate transcription. ABT1 is essential for the recruitment of RNA polymerase II and other transcription factors to the promoter, thereby initiating the transcription process. Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) and DNA with the core region of class II promoters. interaction with TBP and the class II promoter DNA, would activate basal transcription from class II promoters
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