anti- ABT1 antibody

Background

ABT1 (Activator of Basal Transcription 1) is a protein involved in the regulation of gene expression by facilitating the initiation of transcription. It is a component of the pre-initiation complex (PIC), which assembles at the promoter region of genes to initiate transcription. ABT1 is essential for the recruitment of RNA polymerase II and other transcription factors to the promoter, thereby initiating the transcription process. Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) and DNA with the core region of class II promoters. interaction with TBP and the class II promoter DNA, would activate basal transcription from class II promoters