Activator of Basal Transcription 1 (ABT1) Antibody
357.5€ (100 µg)
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Name
Activator of Basal Transcription 1 (ABT1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037021
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ABT1 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Activator of Basal Transcription 1 (ABT1) Immunogen: Recombinant fragment corresponding to 2-272 AA of human ABT1. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 28 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Esf2,hABT1 |
| Background | Antibody anti-ABT1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ABT1 (Activator of Basal Transcription 1) is a protein involved in the regulation of gene expression by facilitating the initiation of transcription. It is a component of the pre-initiation complex (PIC), which assembles at the promoter region of genes to initiate transcription. ABT1 is essential for the recruitment of RNA polymerase II and other transcription factors to the promoter, thereby initiating the transcription process. Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) and DNA with the core region of class II promoters. interaction with TBP and the class II promoter DNA, would activate basal transcription from class II promoters
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