Activator of Basal Transcription 1 (ABT1) Antibody
312€ (60 µl)
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Name
Activator of Basal Transcription 1 (ABT1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx004524
Tested Applications
WB
Description
ABT1 Antibody is a Rabbit Polyclonal antibody against ABT1. Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Activator of Basal Transcription 1 (ABT1) Immunogen: Recombinant fusion protein corresponding to human ABT1 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 31 kDa Observed MW: 31 kDa/36 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULW3 |
| Gene ID | 29777 |
| NCBI Accession | NP_037507.1 |
| Alias | Esf2,hABT1 |
| Background | Antibody anti-ABT1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ABT1 (Activator of Basal Transcription 1) is a protein involved in the regulation of gene expression by facilitating the initiation of transcription. It is a component of the pre-initiation complex (PIC), which assembles at the promoter region of genes to initiate transcription. ABT1 is essential for the recruitment of RNA polymerase II and other transcription factors to the promoter, thereby initiating the transcription process. Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) and DNA with the core region of class II promoters. interaction with TBP and the class II promoter DNA, would activate basal transcription from class II promoters
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