Anterior Gradient Protein 3 (AGR3) Protein
234€ (5 µg)
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Name
Anterior Gradient Protein 3 (AGR3) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx261381
Tested Applications
SDS-PAGE
Description
AGR3 is a recombinant protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | AGR3 |
| Assay Type | Activity: Not tested |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q8TD06 |
| Alias | AG-3,AG3,BCMP11,HAG3,PDIA18 hAG-3 |
| Background | Protein AGR3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AGR3 is structurally related to AGR2 and also functions as a protein disulfide isomerase in the endoplasmic reticulum (ER), supporting protein folding and secretion. AGR3 is expressed predominantly in ciliated epithelial cells of tissues such as the lungs, fallopian tubes, and brain, where it is associated with cilia formation and function. Unlike AGR2, AGR3 has a more specialized role in maintaining epithelial structure and integrity. Dysregulation of AGR3 is implicated in respiratory disorders and has been linked to cancer, particularly in tumors with ciliated origins, such as certain ovarian cancers. AGR3’s role in tumorigenesis is less pronounced than AGR2, but it is being explored as a potential marker for cell differentiation and tissue-specific malignancies.