Anterior Gradient Protein 3 (AGR3) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Anterior Gradient Protein 3 (AGR3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036973
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the AGR3 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Anterior Gradient Protein 3 (AGR3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | AG-3,AG3,BCMP11,HAG3,PDIA18 hAG-3 |
| Background | Antibody anti-AGR3 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
AGR3 is structurally related to AGR2 and also functions as a protein disulfide isomerase in the endoplasmic reticulum (ER), supporting protein folding and secretion. AGR3 is expressed predominantly in ciliated epithelial cells of tissues such as the lungs, fallopian tubes, and brain, where it is associated with cilia formation and function. Unlike AGR2, AGR3 has a more specialized role in maintaining epithelial structure and integrity. Dysregulation of AGR3 is implicated in respiratory disorders and has been linked to cancer, particularly in tumors with ciliated origins, such as certain ovarian cancers. AGR3’s role in tumorigenesis is less pronounced than AGR2, but it is being explored as a potential marker for cell differentiation and tissue-specific malignancies.
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