Anterior Gradient Protein 3 (AGR3) Antibody

Este producto es parte de AGR - Anterior gradient 2, protein disulphide isomerase family member
Anterior Gradient Protein 3 (AGR3) Antibody

Pida mas información

935106861

info@markelab.com

Precio

52€ (10 µg)

Antibody anti-AGR3

proveedor

Abbexa

reference

abx013714

Tested Applications

ELISA, IHC, IF/ICC

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

Rabbit polyclonal antibody against AGR3 protein. Immunogen region is N-terminal.


Background

AGR3 is structurally related to AGR2 and also functions as a protein disulfide isomerase in the endoplasmic reticulum (ER), supporting protein folding and secretion. AGR3 is expressed predominantly in ciliated epithelial cells of tissues such as the lungs, fallopian tubes, and brain, where it is associated with cilia formation and function. Unlike AGR2, AGR3 has a more specialized role in maintaining epithelial structure and integrity. Dysregulation of AGR3 is implicated in respiratory disorders and has been linked to cancer, particularly in tumors with ciliated origins, such as certain ovarian cancers. AGR3’s role in tumorigenesis is less pronounced than AGR2, but it is being explored as a potential marker for cell differentiation and tissue-specific malignancies.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse


immunogen target

Anterior Gradient Protein 3 (AGR3)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, IHC, IF/ICC


purification

Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.


recommended dilution

IHC: 1/50 - 1/100, IF/ICC: 1/100 - 1/500, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.


size 1

10 µg


size 2

100 µg


size 3

200 µg


size 4

300 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

AGR3


dry ice

No


availability

Shipped within 5-10 working days.


alias

AG-3,AG3,BCMP11,HAG3,PDIA18 hAG-3


note

Concentration: 1 mg/ml -


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