Anterior Gradient Protein 3 (AGR3) Antibody

Este producto es parte de AGR - Anterior gradient 2, protein disulphide isomerase family member
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455€ (0.1 mg)

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935106861
info@markelab.com
name
Anterior Gradient Protein 3 (AGR3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx140155
tested applications
WB, IHC, IF/ICC

Description

AGR3 Antibody is a Mouse Monoclonal against AGR3.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Anterior Gradient Protein 3 (AGR3)
Host
Mouse
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Clone ID
S788
Purity
> 95% (SDS-PAGE)
Purification
Purified by Protein A affinity chromatography.
Size 1
0.1 mg
Tested Applications
WB, IHC, IF/ICC
Buffer
PBS solution with 15 mM sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8°C. Do not freeze.
Dry Ice
No
UniProt ID
Q8TD06
Gene ID
155465
Alias
AG-3,AG3,BCMP11,HAG3,PDIA18 hAG-3
Background
Antibody anti-AGR3
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

AGR3 is structurally related to AGR2 and also functions as a protein disulfide isomerase in the endoplasmic reticulum (ER), supporting protein folding and secretion. AGR3 is expressed predominantly in ciliated epithelial cells of tissues such as the lungs, fallopian tubes, and brain, where it is associated with cilia formation and function. Unlike AGR2, AGR3 has a more specialized role in maintaining epithelial structure and integrity. Dysregulation of AGR3 is implicated in respiratory disorders and has been linked to cancer, particularly in tumors with ciliated origins, such as certain ovarian cancers. AGR3’s role in tumorigenesis is less pronounced than AGR2, but it is being explored as a potential marker for cell differentiation and tissue-specific malignancies.

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