Anterior Gradient Protein 3 (AGR3) Antibody
455€ (0.1 mg)
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Name
Anterior Gradient Protein 3 (AGR3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx140155
Tested Applications
WB, IHC, IF/ICC
Description
AGR3 Antibody is a Mouse Monoclonal against AGR3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Anterior Gradient Protein 3 (AGR3) Immunogen: Purified Human AGR3 protein. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | S788 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q8TD06 |
| Gene ID | 155465 |
| Alias | AG-3,AG3,BCMP11,HAG3,PDIA18 hAG-3 |
| Background | Antibody anti-AGR3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AGR3 is structurally related to AGR2 and also functions as a protein disulfide isomerase in the endoplasmic reticulum (ER), supporting protein folding and secretion. AGR3 is expressed predominantly in ciliated epithelial cells of tissues such as the lungs, fallopian tubes, and brain, where it is associated with cilia formation and function. Unlike AGR2, AGR3 has a more specialized role in maintaining epithelial structure and integrity. Dysregulation of AGR3 is implicated in respiratory disorders and has been linked to cancer, particularly in tumors with ciliated origins, such as certain ovarian cancers. AGR3’s role in tumorigenesis is less pronounced than AGR2, but it is being explored as a potential marker for cell differentiation and tissue-specific malignancies.
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